Dexmedetomidine Hydrochloride Injection 2ml: 0.2mg / High Quality

• Customization: Available
• Packaging From: 10 Ampoules/Box
• Packaging: Customization
• Model NO.: injection
• Dosage: Ready
• Transport Package: Shipping
• Specification: 2ml: 0.2mg
• Trademark: brand
• Origin: China

Product Description

Value-added services:
 1) Packaging design by our team
 2) Registration service by our team
 3) Registration dossier available by our team
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------

 

Octreotide Acetate Injection 100mcg/1ml

Composition:

Each 1ml ampoule contains:

• Octreotide Acetate 100mcg

Description:

Octreotide is a synthetic octapeptide analogue of somatostatin, which inhibits the secretion of various hormones, including growth hormone, insulin, glucagon, and vasoactive intestinal peptide (VIP). It has a prolonged duration of action compared to natural somatostatin.

Indications:

Octreotide Acetate Injection is indicated for:

• Acromegaly in patients who are not candidates for surgery or radiation
• Carcinoid tumors (to control symptoms of diarrhea and flushing)
• VIPomas (vasoactive intestinal peptide-secreting tumors)
• Gastrointestinal bleeding from esophageal varices (as an adjunct to endoscopic therapy)
• Postoperative pancreatic fistulas to reduce secretions

Dosage & Administration:

Acromegaly:

• Initial dose: 50-100mcg every 8-12 hours subcutaneously (SC)
• Maintenance dose: Adjust to 300-1500mcg per day, divided into 2-3 doses

Carcinoid Tumors & VIPomas:

• Initial dose: 100-600mcg/day SC, divided into 2-4 doses
• Maintenance dose: Up to 1500mcg/day if needed

Esophageal Variceal Bleeding:

• IV Infusion: 25-50mcg/hour for 5 days
• Bolus dose: 50mcg IV initially, followed by continuous infusion

Postoperative Pancreatic Fistulas:

• 100-200mcg SC every 8-12 hours until fistula output decreases

Renal & Hepatic Impairment:

• Renal impairment: No dose adjustment required
• Hepatic impairment: Use with caution in cirrhosis patients-monitor drug accumulation

Administration:

• SC injection: Preferred route, inject in the upper arm, thigh, or abdomen
• IV infusion: Dilute with saline or dextrose before administration
• Rotate injection sites to prevent irritation

Contraindications:

• Hypersensitivity to Octreotide or its excipients
• Pregnancy & breastfeeding (use only if essential)
• Uncontrolled gallbladder disease

Precautions:

• Monitor blood sugar levels, as Octreotide may cause hypo- or hyperglycemia
• May cause gallstones with long-term use-routine ultrasound monitoring recommended
• Use with caution in cardiovascular disease (may cause bradycardia, arrhythmia)
• Thyroid function changes possible with prolonged treatment-monitor TSH levels

Adverse Reactions:

• Common: Injection site pain, nausea, diarrhea, bloating
• Metabolic: Hypoglycemia, hyperglycemia, gallstone formation
• Cardiovascular: Bradycardia, QT prolongation (rare)
• Serious (rare): Pancreatitis, liver enzyme elevation

Drug Interactions:

• Insulin & Oral Hypoglycemics: May alter glucose metabolism
•  Calcium Channel Blockers: May cause bradycardia
• Ciclosporin: Reduced absorption-monitor levels closely
• Bromocriptine: Increased bioavailability-dose adjustment may be required

Storage Conditions:

• Store at 2-8°C (refrigerated).
• Protect from light.
• Once opened, use within 14 days if stored at room temperature.