Customization: | Available |
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Dosage Form: | Injection |
Dossier: | Ready |
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Generic Name | Furosmide Injection 20mg/2ml |
Strength | 20mg/2ml |
Packing | 10ampoules/box |
Origin | China |
This product is colorless or almost colorless clear liquid.
1. Edematous diseases include congestive heart failure, cirrhosis, kidney disease (nephritis, nephropathy and acute and chronic renal failure caused by various reasons), especially when other diuretic drugs are not effective, the use of this class of drugs may still be effective. Combined with other drugs to treat acute pulmonary edema and acute cerebral edema.
2. Hypertension In the stepped therapy of hypertension, it is not the first choice for the treatment of essential hypertension, but when the efficacy of thiazide drugs is not good, especially when accompanied by renal insufficiency or hypertensive crisis, this class of drugs is especially suitable.
3. Prevention of acute renal failure is used for renal blood perfusion insufficiency caused by various reasons, such as water loss, shock, poisoning, anesthesia accidents and circulatory insufficiency, etc. Timely application while correcting insufficient blood volume can reduce the chance of acute tubular necrosis.
4. Hyperkalemia and hypercalcemia.
5. Dilutive hyponatremia, especially when the blood sodium concentration is below 120mmol/L.
6. Hyperdiuretic hormone secretion (SIADH).
7. Acute drug poisonings such as barbiturates.
Usage and dosage:
1: Adults
(1) Treatment of edematous diseases. In case of emergency or can not be taken orally, can be injected intravenously, starting with 20 to 40mg, if necessary, every 2 hours additional dose, until satisfactory efficacy. Maintenance medication can be administered in separate doses. For acute left heart failure, start with 40mg intravenously and add 80mg per hour if necessary until satisfactory results appear. In the treatment of acute renal failure, 200 ~ 400mg can be added to sodium chloride injection 100m1 intravenously, and the infusion rate is not more than 4mg per minute. If effective, the application can be repeated according to the original dose or adjust the dose as appropriate, and the total daily dose does not exceed 1g. When the diuretic effect is poor, it is not appropriate to increase the dose, so as to avoid renal toxicity, which is unfavorable to the functional recovery of acute renal failure. In the treatment of chronic renal insufficiency, the general daily dose of 40 to 120mg.
(2) In the treatment of hypertensive crisis, the initial 40 to 80mg intravenous injection, accompanied by acute left heart failure or acute renal failure, the dose can be increased as appropriate.
(3) When treating hypercalcemia, it can be injected intravenously, 20 to 80mg at a time.
2. Children
For the treatment of edematous diseases, 1mg/kg intravenous injection is initially given, and 1mg/kg is added every 2 hours if necessary. The maximum dose can be up to 6mg/kg daily. The interval between medications should be extended for newborns.
Matters needing attention:
It is commonly associated with water and electrolyte disorders, especially in large doses or long-term application, such as postural hypotension, shock, hypokalemia, hypochloremia, hypochloremic alkalosis, hyponatremia, hypocalcemia, and related thirst, fatigue, muscle soreness, arrhythmia, etc. In rare cases, there are allergic reactions (including rash, interstitium nephritis, and even cardiac arrest), blurred vision, xanthopia, light sensitivity, dizziness, headache, poor appetite, nausea, vomiting, abdominal pain, diarrhea, pancreatitis, muscular rigidity, etc., skeletal inhibition leading to granulocytopenia, thrombocytopenic purpura and aplastic anemia, liver function impairment, and digital (digital) paresthesia, etc. Hyperglycemia, positive urine sugar, aggravation of existing diabetes, hyperuricemia. Tinnitus and hearing impairment are more common when a large dose of rapid intravenous injection (dose greater than 4 to 15mg per minute), most of them are temporary, and a few are irreversible, especially when used with other ototoxic drugs. In hypercalcemia, it can cause kidney stones. It has also been reported that this drug can aggravate idiopathic edema.