| Generic Name |
Metronidazole Tablet |
| Strength |
500mg |
| Packing |
2*10 Capsules/box |
| Origin |
China |
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Product name:
Metronidazole Tablet
Character:
This product is white or white like tablet.
Indications:
It is used to treat intestinal and parenteral amebiasis (such as amebic liver abscess, pleural amebiasis, etc.). It can also be used to treat vaginal trichomoniasis, balsamiasis and cutaneous leishmaniasis, guinea worm infection, etc. At present, it is also widely used in the treatment of anaerobic bacteria infection.
Adverse reactions:
Adverse reactions occurred in 15%-30% of cases, and gastrointestinal reactions were the most common, including nausea, vomiting, loss of appetite, and abdominal cramps, which generally did not affect treatment. Nervous system symptoms include headache, vertigo, occasional paresthesia, limb numbness, ataxia, multiple neuritis, etc. Large doses can cause convulsions. In a small number of cases, urticaria, flushing, pruritus, cystitis, dysuria, metallic taste in the mouth and leukopenia were reversible and recovered spontaneously after withdrawal.
Pharmacology and toxicology:
This product is a nitroimidazole derivative, which can inhibit the REDOX reaction of Amoeba and break the nitrogen chain of amoeba. In vitro tests have shown that when the concentration of the drug is 1 ~ 2mg/L, the morphology of amoeba histolytica can be changed in 6 ~ 20 hours, and all are killed within 24 hours, and the concentration of 0.2mg/L can kill amoeba histolytica within 72 hours. This product has a strong killing effect on trichomonas, its mechanism is not clear.
Metronidazole has a killing effect on anaerobic microorganisms, and the metabolites generated when it is reduced in the human body also have an anti-anaerobic effect, inhibiting the synthesis of deoxyribonucleic acid of bacteria, thereby interfering with the growth and reproduction of bacteria, and ultimately causing bacterial death.
It is carcinogenic to some animals.
Storage:
Keep out of light and sealed.
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