Terlipressin for Injection 80mg / High Quality

• Customization: Available
• Packaging From: 5+5/Box.
• Packaging: Customization
• Model NO.: Powder for injection
• Dosage: Ready
• Certified: GMP
• Transport Package: Shipping
• Specification: 80mg
• Trademark: Customization
• Origin: China
• Production Capacity: 10000000

Product Description

Value-added services:
 1) Packaging design by our team
 2) Registration service by our team
 3) Registration dossier available by our team
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Terlipressin for Injection

Composition:

Each vial contains:

• Terlipressin Acetate equivalent to Terlipressin 1mg or 2mg
• Excipients: (e.g., sodium chloride, water for injection)

Description:

Terlipressin is a vasopressin analog with potent vasoconstrictive effects. It is primarily used in emergency settings for conditions related to circulatory shock and portal hypertension.

Indications:

Terlipressin for Injection is indicated for:

• Bleeding esophageal varices (BEV) in patients with liver cirrhosis
• Hepatorenal syndrome (HRS) Type 1
• Refractory hypotension in septic shock (off-label use)

Dosage & Administration:

For Bleeding Esophageal Varices (BEV):

• Initial dose: 2mg IV bolus every 4-6 hours
• Maintenance dose: 1mg IV every 4-6 hours until bleeding control (max 48 hours)

For Hepatorenal Syndrome (HRS Type 1):

• Initial dose: 0.5-1mg IV every 4-6 hours
• Titration: Increase up to 2mg every 4 hours if no response after 3 days
• Duration: Usually 3-14 days, depending on kidney function improvement

Administration:

• Given intravenously (IV) by slow injection over 2-5 minutes
• Can be diluted in normal saline (NS) or dextrose 5% (D5W)

Contraindications:

• Hypersensitivity to Terlipressin or vasopressin analogs
• Severe cardiac disease (e.g., coronary artery disease, uncontrolled hypertension)
• Severe peripheral vascular disease
• Pregnancy (Category C) - Risk of uterine contractions and fetal distress

Precautions:

• Cardiovascular risks: May cause bradycardia, arrhythmias, or severe hypertension.
• Renal monitoring: Monitor urine output and kidney function.
• Electrolyte imbalance: May cause hyponatremia or hypokalemia.
• Use in elderly patients: Increased risk of ischemic events.

Adverse Reactions:

• Common: Abdominal cramps, nausea, diarrhea, paleness, headache
• Cardiovascular: Hypertension, bradycardia, arrhythmias
• Serious (rare): Myocardial infarction, mesenteric ischemia, peripheral ischemia

Drug Interactions:

• Diuretics: Increased risk of hyponatremia.
• Dopamine or norepinephrine: Risk of excessive vasoconstriction.

Storage Conditions:

• Store below 25°C.
• Protect from light and moisture.
• Reconstituted solution should be used immediately.