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Quality Standard: | Bp, USP |
Ctd Dossier: | Available |
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Generic Name | Deproteinized Calf Blood Extractives Injection |
Strength | 200mg/5ml |
Packing | 5 amps/box |
Origin | China |
Component:
The main ingredient of this product is deproteinized calf blood extract.
Character:
Solution for injection.
It is a pale yellow clear liquid.
Indications:
Disorders of brain circulation and nutrition (ischemic attacks, craniocerebral trauma)
· Peripheral blood flow (motor and venous) disorders and sequelae caused by these disorders (arterial vascular diseases, leg ulcers)
· Skin grafting
· Burns, scalds, erosion
· Wound healing disorders: bedsores and wounds heal slowly
· Skin and mucous membrane damage caused by radiation
Precautions:
1. This product is a hypertonic solution, so it should be used slowly for intramuscular injection, not more than 5 ml (half) each time.
2. This product for infusion must be added to isotonic saline, 5% glucose solution.
3. When this product is mixed with other infusion or injection, even if the mixture is clear, it cannot rule out the physical and chemical changes that may arise from drug interactions. For the above reasons, this product should not be mixed with other injections.
4. This product is light yellow, the shade depends on the material used at the beginning of the preparation. Therefore, there is a small difference in color between one batch of drugs and another batch, but it does not affect the efficacy. Do not use if the solution is cloudy or has visible particles.
5. Experimental injection is recommended because of the possibility of allergy.
Pharmacology and toxicology:
This product can cause an increase in organ-independent cellular energy metabolism. This activity can be confirmed by measuring increased uptake of glucose and oxygen. These two effects are interrelated and can cause an increase in the amount of ATP turnover, thus providing more energy in the cell. When the normal function of energy metabolism is incomplete or impaired (hypoxia, matrix deficiency) and the demand for energy is increased (repair, regeneration), this product promotes energy-dependent functional metabolism and retention metabolism processes, and a secondary increase in blood supply is seen.
Acute, subacute, and chronic toxicity tests administered orally, intradermal, subcutaneous, and intravenously with single and multiple doses up to 30-40 times the human equivalent showed virtually no local or systemic toxicity. This product is not toxic to fertility and embryos, nor has it caused teratogenic effect, mutagenicity or carcinogenic effect.