Lincomycin Hydrochloride Injection 600mg/2ml / High Quality

• Customization: Available
• Packaging From: 1 Vial /Box
• Packaging: Customization
• Model NO.: injection
• Dosage: Ready
• Certified: GMP
• Transport Package: Shipping
• Specification: 2ml: 600mg
• Trademark: Customization
• Origin: China

Product Description

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Lincomycin Hydrochloride Injection 600mg/2mL (300 mg/mL)

Composition:

Each 2mL ampoule contains:

• Lincomycin Hydrochloride - 600 mg (300 mg/mL)
• Excipients: Sodium chloride, Water for injection

Description:

Lincomycin Hydrochloride is a lincosamide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. It is effective against Gram-positive bacteria, including Staphylococcus, Streptococcus, and some anaerobic bacteria.

Indications:

Lincomycin Injection is indicated for the treatment of serious infections caused by susceptible strains of bacteria, including:

• Respiratory tract infections (pneumonia, bronchitis)
• Skin and soft tissue infections (cellulitis, abscesses)
• Bone and joint infections (osteomyelitis, septic arthritis)
• Severe bacterial infections when penicillins are not suitable

Dosage & Administration:

Intramuscular (IM) Injection:

• Adults: 600 mg every 12-24 hours
• Children (>1 month): 10 mg/kg every 12-24 hours

Intravenous (IV) Infusion:

• Adults: 600 mg-1 g IV every 8-12 hours
• Children (>1 month): 10-20 mg/kg IV every 8-12 hours
• Severe infections: Up to 8 g/day in divided doses

Administration:

• IV infusion: Dilute with at least 100 mL of compatible fluid and administer over 60 minutes
• Do not administer IV push (risk of cardiac toxicity)

Contraindications:

• Hypersensitivity to Lincomycin or Clindamycin
• History of colitis or Clostridium difficile infection

Precautions:

• Use with caution in patients with:
  • Renal or hepatic impairment (dose adjustment needed)
  • Gastrointestinal diseases (risk of colitis)

Adverse Reactions:

• Common: Nausea, vomiting, diarrhea, rash
• Serious: Pseudomembranous colitis, liver dysfunction, anaphylaxis

Drug Interactions:

• Neuromuscular blockers: Increased muscle relaxant effect
• Macrolides (e.g., Erythromycin): Antagonistic effect
• Warfarin: Increased risk of bleeding

Overdose & Management:

• Symptoms: Severe diarrhea, liver toxicity
• Treatment: Supportive care, IV fluids, discontinue if colitis occurs

Storage Conditions:

• Store below 25°C
• Protect from light
• Do not freeze