Erythromycin Lactobionate for Injection 1g / High Quality

• Customization: Available
• Packaging From: 10 Vials /Box
• Packaging: Customization
• Model NO.: Powder for injection
• Dosage: Ready
• Certified: GMP
• Transport Package: Shipping
• Specification: 1g
• Trademark: Customization
• Origin: China

Product Description

Value-added services:
 1) Packaging design by our team
 2) Registration service by our team
 3) Registration dossier available by our team
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Erythromycin Lactobionate for Injection 1g

Composition:

Each vial contains:

• Erythromycin Lactobionate - 1g (equivalent to 1g Erythromycin base)

Description:

Erythromycin is a macrolide antibiotic with broad-spectrum activity against gram-positive and some gram-negative bacteria. It inhibits bacterial protein synthesis, making it effective in treating a variety of infections.

Indications:

Erythromycin Lactobionate for Injection is used for the treatment of infections caused by erythromycin-sensitive organisms, including:

• Respiratory tract infections (pneumonia, pertussis, bronchitis, Legionnaires' disease)
• Skin and soft tissue infections (impetigo, erysipelas, abscesses)
• Diphtheria (as adjunct to antitoxin)
• Syphilis (in penicillin-allergic patients)
• Pelvic inflammatory disease (PID)
• Severe streptococcal infections

Dosage & Administration:

Intravenous (IV) Use Only

• Adults & children >12 years: 15-20mg/kg/day, divided into 6-hourly doses
• Severe infections: Up to 4g per day
• Children (<12 years): 20-50mg/kg/day in divided doses

Reconstitution & Administration:

1. Reconstitute the 1g vial with 20mL sterile water for injection.
2. Further dilute in 250-500mL of normal saline (0.9% NaCl) or 5% dextrose.
3. Administer via slow IV infusion over 60 minutes.

DO NOT administer as an IV bolus or IM injection.

Contraindications:

• Hypersensitivity to erythromycin or other macrolides
• Severe liver disease
• Concurrent use with drugs that prolong the QT interval (e.g., cisapride, terfenadine, pimozide, astemizole)

Precautions:

• Use with caution in patients with liver impairment
• Monitor for signs of Clostridium difficile-associated diarrhea (CDAD)
• May cause QT prolongation and arrhythmias

Adverse Reactions:

• Common: Nausea, vomiting, diarrhea, abdominal pain
• Serious: Hepatotoxicity, QT prolongation, allergic reactions (anaphylaxis, rash, angioedema)

Drug Interactions:

• Warfarin: Increased bleeding risk
• Statins (simvastatin, lovastatin): Increased risk of myopathy/rhabdomyolysis
• Theophylline, digoxin, cyclosporine: Increased serum levels

Overdose & Management:

• Symptoms: Severe nausea, vomiting, cardiac arrhythmias
• Treatment: Supportive care, ECG monitoring, IV fluids

Storage Conditions:

• Store below 25°C, protect from light and moisture
• Use reconstituted solution immediately or within 8 hours (at room temperature)