Valsartan Dispersible Tablets 80mg (7tabs/box)

• Dossier: Ctd
• Transport Package: Free
• Specification: 80mg
• Trademark: Sinolead
• Origin: China
• Model NO.: tablets

Product Description

 

Basic Info.

 

Generic Name	Valsartan Dispersible Tablets 80mg
Strength	80mg
Packing	7tabs/box
Origin	China

Component:
Valsartan.

Character:

This product is white.

Indications:

Treatment of mild and moderate essential hypertension.
 

Usage and dosage:

Recommended dose: 80mg once a day. The dose was not related to race, age, or sex. It can be taken with a meal or on an empty stomach (see absorption). It is recommended to take the medicine at the same time every day (e.g. in the morning). The exact antihypertensive effect was achieved within 2 weeks and the maximum effect was achieved after 4 weeks. If the antihypertensive effect is not satisfactory, the daily dose can be increased to 160mg, or a diuretic can be added. Patients with renal insufficiency (contraindicated for severe renal failure) and non-bile duct derived liver insufficiency without cholestasis do not need to adjust the dose.

Valsartan can be used in combination with other antihypertensive drugs.

Matters needing attention:

Low sodium and/or low blood volume

In rare cases, patients with severe sodium deficiency and/or low blood volume (e.g., large doses of diuretics) may experience symptomatic hypotension at the beginning of treatment with this product. Low sodium and/or low blood volume should be corrected, or diuretics reduced, before medication. If hypotension occurs, the patient should be placed on his or her back and given intravenous saline if necessary. Blood pressure stabilized after the resumption of this product treatment.

Renal artery stenosis

12 patients with secondary renal vascular hypertension caused by unilateral renal artery stenosis took this product for 4 days, and there was no significant change in renal hemodynamics, creatinine, urea nitrogen (BUN). Because other drugs acting on RAAS may raise BUN and creatinine in patients with unilateral or bilateral renal artery stenosis, monitoring is recommended to ensure safety.

Renal insufficiency

Patients with renal insufficiency do not need to adjust the dose.

Liver dysfunction

Patients with hepatic insufficiency do not need to adjust the dose.

The dose of valsartan should not exceed 80mg/ day in patients with mild to moderate hepatic insufficiency.

Valsartan is primarily excreted from the bile in prototype form, with reduced excretion in patients with biliary obstruction (see pharmacokinetics), and particular caution should be exercised in such patients.

As with other antihypertensive drugs, patients should be careful when driving and operating machinery.