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Dossier: | Ctd |
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Generic Name | Valsartan Dispersible Tablets 80mg |
Strength | 80mg |
Packing | 7tabs/box |
Origin | China |
This product is white.
Treatment of mild and moderate essential hypertension.
Matters needing attention:
Low sodium and/or low blood volume
In rare cases, patients with severe sodium deficiency and/or low blood volume (e.g., large doses of diuretics) may experience symptomatic hypotension at the beginning of treatment with this product. Low sodium and/or low blood volume should be corrected, or diuretics reduced, before medication. If hypotension occurs, the patient should be placed on his or her back and given intravenous saline if necessary. Blood pressure stabilized after the resumption of this product treatment.
Renal artery stenosis
12 patients with secondary renal vascular hypertension caused by unilateral renal artery stenosis took this product for 4 days, and there was no significant change in renal hemodynamics, creatinine, urea nitrogen (BUN). Because other drugs acting on RAAS may raise BUN and creatinine in patients with unilateral or bilateral renal artery stenosis, monitoring is recommended to ensure safety.
Renal insufficiency
Patients with renal insufficiency do not need to adjust the dose.
Liver dysfunction
Patients with hepatic insufficiency do not need to adjust the dose.
The dose of valsartan should not exceed 80mg/ day in patients with mild to moderate hepatic insufficiency.
Valsartan is primarily excreted from the bile in prototype form, with reduced excretion in patients with biliary obstruction (see pharmacokinetics), and particular caution should be exercised in such patients.
As with other antihypertensive drugs, patients should be careful when driving and operating machinery.