Parecoxib is used for the short-term treatment of pain in adults after an operation. It is one of a family of medicines called COX-2 inhibitors (this is short for cyclo-oxygenase-2 inhibitors). Pain and swelling are sometimes caused by substances in the body called prostaglandins. Parecoxib works by lowering the amount of these prostaglandins.
How to use Parecoxib
Parecoxib will be given to you by a doctor or nurse. They will dissolve the powder before giving you the injection, and will inject the solution into a vein or a muscle. The injection may be given rapidly and directly into a vein or into an existing intravenous line (a thin tube running into a vein), or it can be given slowly and deeply into a muscle. You will only be given Parecoxib for short periods, and only for pain relief.
The usual dose to start with is 40mg.
You may be given another dose - either 20mg or 40mg - 6 to 12 hours after the first one.
You will not be given more than 80mg in 24 hours.
Some people may be given lower doses:
· People with liver problems.
· People with severe kidney problems.
· Patients over 65 who weigh less than 50kg.
· People taking fluconazole.
If Parecoxib is used with strong pain killers (called opioid analgesics) such as morphine the dose of Parecoxib will be the same as explained above.
If you are given more Parecoxib than you should you may experience side-effects that have been reported with recommended doses.
If you have any further questions on the use of this medicine, ask your doctor or nurse.
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