Ibuprofen Injection 800mg / High Quality

• Customization: Available
• Packaging From: 1 Vial /Box
• Packaging: Customization
• Model NO.: injection
• Dosage: Ready
• Certified: GMP
• Transport Package: Shipping
• Specification: 800mg
• Trademark: Customization
• Origin: China

Product Description

Value-added services:
 1) Packaging design by our team
 2) Registration service by our team
 3) Registration dossier available by our team
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Ibuprofen Injection 800mg

Composition:

Each (X ml) contains:

• Ibuprofen .........… 800mg
• Excipients .........… (as required)

Description:

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits analgesic, anti-inflammatory, and antipyretic properties by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, reducing prostaglandin synthesis.

Indications:

Ibuprofen Injection is indicated for:

• Moderate to severe pain (alone or with opioids)
• Fever reduction
• Postoperative pain management
• Inflammatory conditions such as arthritis

Dosage & Administration:

Intravenous Infusion Only

• Adults: 400-800mg every 6 hours, administered over at least 30 minutes
• Maximum daily dose: 3,200mg
• Pediatrics (if applicable): 10mg/kg every 6 hours, not exceeding 40mg/kg/day
• Use lowest effective dose for shortest duration possible

Contraindications:

• Hypersensitivity to ibuprofen, aspirin, or other NSAIDs
• Active peptic ulcer disease or gastrointestinal (GI) bleeding
• Severe renal or hepatic impairment
• Coronary artery bypass graft (CABG) surgery perioperative pain
• History of NSAID-induced asthma or anaphylaxis

Precautions:

• Increased risk of cardiovascular events (stroke, myocardial infarction) with prolonged use
• May cause gastrointestinal bleeding, ulceration, and perforation
• Use with caution in renal impairment (monitor creatinine levels)
• Avoid in late pregnancy (≥30 weeks gestation) due to risk of premature ductus arteriosus closure

Adverse Reactions:

• Common: Nausea, vomiting, dizziness, headache, GI discomfort
• Serious: GI bleeding, liver dysfunction, kidney injury, hypertension, anaphylaxis

Drug Interactions:

• Increased risk of bleeding with anticoagulants (e.g., warfarin, heparin)
• Reduced antihypertensive effect of ACE inhibitors,  and diuretics
• Increased nephrotoxicity with aminoglycosides and cyclosporine
• Avoid concomitant use with other NSAIDs

Overdose & Management:

• Symptoms: Nausea, vomiting, epigastric pain, renal failure, metabolic acidosis
• Treatment: Supportive care, activated charcoal (if early ingestion), IV fluids, and correction of electrolyte imbalances

Storage Conditions:

• Store below 25°C, protect from light
• Do not freeze