Pemetrexed Disodium for Injection 0.2g

• Customization: Available
• Package: 1vial/Box
• Composition: Pemetrexed Disodium
• Model NO.: 0.2g
• Transport Package: Free
• Specification: 0.2g/vial
• Trademark: Sinolead
• Origin: China

Product Description

Product	Dose	Package
Pemetrexed Disodium For Injection	0.2g	1vial/box

• Pemetrexed Disodium for Injection (200 mg) is an antifolate chemotherapy agent used primarily to treat certain types of cancer, particularly in the lungs and pleura. It works by inhibiting folate-dependent enzymes critical for DNA and RNA synthesis, slowing down the growth and spread of cancer cells.

Indications:
 

Pemetrexed is commonly used for:

• Non-Small Cell Lung Cancer (NSCLC): As a first-line or maintenance therapy, usually in combination with other chemotherapy agents like cisplatin.
• Malignant Pleural Mesothelioma: In combination with cisplatin, for unresectable or metastatic cases.

Administration:

• Infusion: Administered intravenously over 10 minutes.
• Folic Acid and Vitamin B12 Supplementation: Patients typically take oral folic acid (400-1000 mcg daily) and receive intramuscular vitamin B12 (1000 mcg) injections every 9 weeks to reduce toxic effects.

Precautions:

• Renal Function Monitoring: Pemetrexed is primarily excreted by the kidneys, so renal function should be assessed before each dose.
• Pregnancy and Breastfeeding: Contraindicated due to potential harm to the fetus or infant.
• Avoid NSAIDs: Nonsteroidal anti-inflammatory drugs (NSAIDs) may interfere with pemetrexed excretion, especially in patients with kidney impairment.