Ampicillin Sodium and Sulbactam Sodium for Injection / High Quality

• Customization: Available
• Packaging From: 1+1/Box; 10 Vials /Box
• Packaging: Customization
• Model NO.: Powder for injection
• Dosage: Ready
• Certified: GMP
• Transport Package: Shipping
• Specification: 1.5g
• Trademark: Customization
• Origin: China

Product Description

Value-added services:
 1) Packaging design by our team
 2) Registration service by our team
 3) Registration dossier available by our team
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Product Name

Ampicillin Sodium and Sulbactam Sodium for Injection

 

Active Ingredients

Each vial contains:

• Ampicillin Sodium: Equivalent to 1g (1000mg) of Ampicillin.

• Sulbactam Sodium: Equivalent to 0.5g (500mg) of Sulbactam.

 

Description

Ampicillin Sodium and Sulbactam Sodium for Injection is a combination antibiotic medication. Ampicillin is a penicillin-class antibiotic that fights bacteria, while sulbactam is a beta-lactamase inhibitor that prevents bacterial resistance. This combination enhances the effectiveness of the treatment against a broader range of bacteria, including beta-lactamase-producing strains. The injectable form is suitable for severe infections or when oral administration is not feasible.

 

Indications

This medication is used to treat infections caused by susceptible bacteria, including:

• Respiratory tract infections (e.g., pneumonia, bronchitis)

• Intra-abdominal infections (e.g., peritonitis)

• Skin and soft tissue infections (e.g., cellulitis, abscesses)

• Urinary tract infections (e.g., pyelonephritis)

• Gynecological infections (e.g., endometritis, pelvic inflammatory disease)

• Septicemia

 

Dosage and Administration

• Adults:

  • Mild to moderate infections: 1.5g (1g ampicillin + 0.5g sulbactam) every 6-8 hours, intravenously or intramuscularly.

  • Severe infections: 3g (2g ampicillin + 1g sulbactam) every 6 hours, intravenously.

• Children:

  • Dosage: 150mg/kg body weight per day (based on ampicillin component), divided into 3-4 doses, intravenously or intramuscularly.

• Administration: Reconstitute the vial with sterile water for injection or compatible IV fluids. Administer by slow intravenous injection or infusion over 15-30 minutes, or as an intramuscular injection.

 

Side Effects

Common side effects may include:

• Gastrointestinal disturbances (e.g., nausea, vomiting, diarrhea)

• Allergic reactions (e.g., rash, itching)

• Injection site reactions (e.g., pain, redness)

Serious side effects (e.g., severe allergic reactions, Clostridioides difficile-associated diarrhea) are rare but require immediate medical attention.

 

Contraindications

• Hypersensitivity to ampicillin, sulbactam, other penicillins, or any component of the formulation.

• History of severe allergic reactions (e.g., anaphylaxis) to beta-lactam antibiotics.

 

Precautions

• Consult a doctor before use if you have a history of kidney disease, mononucleosis, or allergies.

• Regular monitoring of kidney and liver function is recommended during prolonged use.

• Discontinue use and consult a doctor if severe diarrhea or abdominal pain occurs.

 

Drug Interactions

• Probenecid: May increase ampicillin blood levels.

• Oral contraceptives: May reduce contraceptive efficacy.

• Methotrexate: May increase the risk of methotrexate toxicity.

 

Storage

• Before reconstitution: Store in a cool, dry place (below 25°C), away from direct sunlight.

• After reconstitution: Use immediately or store in the refrigerator (2-8°C) for up to 24 hours. Do not freeze.