Cimetidine Injection 2ml: 200mg / High Quality

• Customization: Available
• Packaging From: 10 Ampoules/Box
• Packaging: Customization
• Model NO.: injection
• Dosage: Ready
• Transport Package: Shipping
• Specification: 2ml: 200mg
• Trademark: brand
• Origin: China

Product Description

Value-added services:
 1) Packaging design by our team
 2) Registration service by our team
 3) Registration dossier available by our team
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Cimetidine Injection 2ml:200mg

Composition:

Each 2 mL ampoule contains:

• Cimetidine 200 mg

Description:

Cimetidine is a histamine H2-receptor antagonist (H2-blocker) that inhibits gastric acid secretion. It is used in the treatment and prevention of peptic ulcers, gastroesophageal reflux disease (GERD), and other acid-related conditions.

Indications:

Cimetidine Injection is indicated for:

• Peptic ulcer disease (gastric and duodenal ulcers)
• Gastroesophageal reflux disease (GERD)
• Zollinger-Ellison Syndrome and other hypersecretory conditions
• Prevention of stress ulcers in critically ill patients
• Aspiration pneumonitis prophylaxis in surgical patients

Dosage & Administration:

Recommended Dosage (Adults):

• Peptic Ulcer Disease & GERD: 200 mg IV every 6 hours, or continuous infusion of 37.5 mg/hour
• Zollinger-Ellison Syndrome: 300 mg IV every 6 hours, adjust based on acid output
• Aspiration Pneumonitis Prophylaxis: 300 mg IV 1 hour before anesthesia

Administration:

• Intravenous (IV) administration only
• IV bolus: Dilute in 20 mL of 0.9% sodium chloride (NaCl) and administer slowly over 5 minutes
• IV infusion: Dilute in 100 mL of NaCl or 5% dextrose, infuse over 15-30 minutes

Dose Adjustments:

• Renal Impairment: Reduce dose in severe kidney disease (CrCl < 30 mL/min)
• Elderly Patients: Use lower doses as clearance may be reduced

Contraindications:

• Hypersensitivity to Cimetidine or other H2-blockers
• Severe renal or hepatic dysfunction (use with caution)

Precautions:

• Long-term use may lead to:
  • Vitamin B12 deficiency
  • Increased risk of pneumonia
• May cause gynecomastia with prolonged use
• Can interact with multiple drugs (inhibits CYP450 enzymes)

Adverse Reactions:

• Common: Headache, dizziness, diarrhea, rash
• Serious: Bradycardia, confusion (especially in elderly patients), liver enzyme elevation

Drug Interactions:

• Warfarin, Theophylline, Phenytoin: Increased drug levels-monitor closely
• Ketoconazole: Reduced absorption-take separately
• Procainamide: Increased risk of toxicity

Overdose & Management:

• Symptoms: Hypotension, confusion, bradycardia
• Treatment: Supportive care, IV fluids, symptomatic treatment

Storage Conditions:

• Store below 25°C, protect from light
• Use immediately after opening