Ampicillin Sodium and Cloxacillin for Injection 500mg / High Quality

• Customization: Available
• Packaging From: 10 Vials /Box
• Packaging: Customization
• Model NO.: Powder for injection
• Dosage: Ready
• Certified: GMP
• Transport Package: Shipping
• Specification: 500mg
• Trademark: Customization
• Origin: China

Product Description

Value-added services:
 1) Packaging design by our team
 2) Registration service by our team
 3) Registration dossier available by our team
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Ampicillin Sodium and Cloxacillin Sodium for Injection 500mg

Composition:

Each vial contains:

• Ampicillin Sodium - 250mg
• Cloxacillin Sodium - 250mg

Description:

Ampicillin Sodium and Cloxacillin Sodium for Injection is a broad-spectrum penicillin antibiotic combination.

• Ampicillin is a beta-lactam antibiotic effective against Gram-positive and Gram-negative bacteria.
• Cloxacillin is a penicillinase-resistant antibiotic, providing additional coverage against penicillinase-producing staphylococci.

Indications:

This combination is used to treat bacterial infections caused by susceptible organisms, including:

• Respiratory tract infections (pneumonia, bronchitis, tonsillitis)
• Skin and soft tissue infections
• Bone and joint infections (osteomyelitis)
• Urinary tract infections (UTIs)
• Septicemia and endocarditis
• Post-operative infections

Dosage & Administration:

Intramuscular (IM) or Intravenous (IV) Injection

• Adults: 500mg to 1g every 6-8 hours, depending on severity
• Children: 50-100mg/kg/day in divided doses
• Neonates: 25-50mg/kg/day in divided doses

Reconstitution & Administration:

• IV injection: Dissolve in 10mL sterile water for injection, administer slowly over 3-5 minutes
• IM injection: Dissolve in 2mL sterile water for injection, inject deep intramuscularly

Contraindications:

• Hypersensitivity to penicillins or beta-lactam antibiotics
• Severe renal impairment (without dosage adjustment)
• History of severe allergic reactions (e.g., anaphylaxis) to beta-lactams

Precautions:

• Monitor renal and hepatic function during prolonged use
• Use with caution in patients with a history of allergies or asthma
• Avoid in patients with infectious mononucleosis (risk of rash)

Adverse Reactions:

• Common: Nausea, vomiting, diarrhea, rash
• Serious: Anaphylaxis, Stevens-Johnson Syndrome (rare), Clostridioides difficile-associated diarrhea

Drug Interactions:

• Probenecid: Increases blood levels of ampicillin and cloxacillin
• Oral contraceptives: May reduce efficacy
• Aminoglycosides: Potential inactivation if mixed in the same IV solution

Overdose & Management:

• Symptoms: Seizures, nephrotoxicity, severe diarrhea
• Treatment: Supportive care, hemodialysis if necessary

Storage Conditions:

• Store below 25°C
• Protect from moisture and light
• Use reconstituted solution immediately