Paracetamol Tablets 500mg / High Quality

• Customization: Available
• Certified: GMP
• Dossier: Ctd
• Model NO.: Tablet
• Packing: Customization
• Package: 30 Tablets / Box
• Transport Package: Box
• Specification: 400mg
• Trademark: Sinolead
• Origin: China

Product Description

Paracetamol Tablets 500mg

Composition:

Each tablet contains:

• Paracetamol 500mg

Description:

Paracetamol (also known as Acetaminophen) is a widely used analgesic (pain reliever) and antipyretic (fever reducer). It is effective for treating mild to moderate pain and fever, with minimal gastrointestinal side effects compared to NSAIDs.

Indications:

Paracetamol is indicated for the relief of pain and fever, including:

• Headache and migraine
• Toothache and dental pain
• Muscle pain and backache
• Arthritis and joint pain
• Menstrual pain (dysmenorrhea)
• Cold, flu, and fever symptoms

Dosage & Administration:

Adults and Children Over 12 Years:

• 500-1000mg (1-2 tablets) every 4 to 6 hours as needed
• Maximum daily dose: 4000mg (8 tablets) in 24 hours

Children (6-12 years):

• 250-500mg every 4 to 6 hours as needed
• Maximum daily dose: 2000mg (4 tablets) in 24 hours

Children Under 6 Years:

• Use only under medical supervision (consider liquid formulations)

Administration:

• Take orally with water
• Can be taken with or without food
• Do not exceed the recommended dose

Contraindications:

• Hypersensitivity to Paracetamol or any excipient in the formulation
• Severe liver disease or acute liver failure

Precautions:

• Liver Toxicity: Avoid exceeding the maximum dose, especially in patients with liver disease, chronic alcoholism, or long-term Paracetamol use
• Renal Impairment: Use with caution in patients with severe kidney disease
• Alcohol Use: Avoid excessive alcohol consumption, as it increases the risk of liver damage
• Use in Pregnancy and Breastfeeding: Generally safe, but should be used at the lowest effective dose for the shortest duration

Adverse Reactions:

• Common: Nausea, vomiting, rash
• Rare but serious: Liver toxicity, Stevens-Johnson syndrome, hematologic disorders (thrombocytopenia, neutropenia)

Drug Interactions:

• Alcohol & Hepatotoxic Drugs: Increased risk of liver damage
• Warfarin & Anticoagulants: Prolonged use may increase bleeding risk-monitor INR closely
• Rifampicin, Carbamazepine, Phenytoin: May reduce Paracetamol effectiveness by increasing metabolism

Overdose & Management:

• Symptoms of Overdose: Nausea, vomiting, abdominal pain, liver failure
• Treatment:
  • Seek immediate medical attention
  • Activated charcoal if within 1 hour of overdose
  • N-acetylcysteine (NAC) is the antidote-administer as soon as possible

Storage Conditions:

• Store below 25°C, in a dry place
• Protect from moisture and direct sunlight