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Amoxicillin and Clavulanate Potassium for Oral Suspension
Each 5mL of reconstituted suspension contains:
Amoxicillin: 125mg, 250mg, or 400mg
Clavulanate Potassium: 31.25mg, 62.5mg, or 57mg (equivalent to clavulanic acid)
Amoxicillin and Clavulanate Potassium for Oral Suspension is a combination antibiotic medication. Amoxicillin is a penicillin-class antibiotic that fights bacteria, while clavulanate potassium is a beta-lactamase inhibitor that prevents bacterial resistance. This combination enhances the effectiveness of the treatment against a broader range of bacteria. The oral suspension form is particularly suitable for pediatric patients or those who have difficulty swallowing tablets.
This medication is used to treat infections caused by susceptible strains of bacteria, including:
Respiratory tract infections (e.g., sinusitis, bronchitis, pneumonia)
Urinary tract infections (e.g., cystitis, pyelonephritis)
Skin and soft tissue infections (e.g., cellulitis, abscesses)
Ear, nose, and throat infections (e.g., otitis media, tonsillitis)
Bone and joint infections
Adults and children ≥40kg:
125mg/31.25mg per 5mL: 10mL every 8 hours.
250mg/62.5mg per 5mL: 5mL every 8 hours.
400mg/57mg per 5mL: 5mL every 12 hours.
Children <40kg: Dosage is based on body weight (typically 20-45mg/kg/day of amoxicillin component, divided into 2-3 doses).
Administration: Shake the bottle well before use. Use the provided measuring device to ensure accurate dosing. Can be taken with or without food, but administration at the start of a meal may improve absorption and reduce gastrointestinal side effects.
Common side effects may include:
Gastrointestinal disturbances (e.g., nausea, vomiting, diarrhea)
Allergic reactions (e.g., rash, itching)
Headache or dizziness
If severe side effects occur (e.g., severe diarrhea, difficulty breathing, swelling of the face or throat), discontinue use and seek medical attention immediately.
Hypersensitivity to penicillin, cephalosporins, or any component of the formulation.
History of cholestatic jaundice or liver dysfunction associated with this medication.
Consult a doctor before use if you have a history of kidney disease, liver disease, or mononucleosis.
Prolonged use may lead to the development of resistant bacteria. Use only as prescribed.
Not effective against viral infections (e.g., colds, flu).
Probenecid: May increase amoxicillin blood levels.
Oral contraceptives: May reduce contraceptive efficacy.
Methotrexate: May increase the risk of methotrexate toxicity.
Other antibiotics: May cause antagonistic effects.
Before reconstitution: Store in a cool, dry place (below 25°C), away from direct sunlight.
After reconstitution: Store in the refrigerator (2-8°C) and use within 7-10 days. Shake well before each use.
24 months from the date of manufacture (before reconstitution).
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