Magnesium Sulfate Injection 10ml: 2.5g (5AMPS/box)

• Dossier: Ctd
• GMP: Chinese GMP
• Transport Package: Free
• Specification: 10ml: 2.5g
• Trademark: Sinolead
• Origin: China
• Model NO.: Injection

Product Description

Generic Name	Magnesium Sulfate Injection
Strength	10ml:2.5g
Packing	5amps/box
Origin	China

Component:
Magnesium Sulfate.

Character:

This product is colorless transparent liquid.

Indications:

It can be used as an anticonvulsant. It is often used for pregnancy-induced hypertension. It lowers blood pressure, treats preeclampsia and eclampsia, and is also used to treat premature births.
 

Usage and dosage:

1. Treatment of moderate to severe gestational hypertension, preeclampsia and eclampsia

The first dose was 2.5-4G, diluted with 25% glucose injection 20ml, slowly injected intravenously within 5 minutes, and then maintained by 1-2g intravenous drip every hour. The 24-hour total was 30g and was monitored based on knee tendon reflexes, breathing and urine volume.

2. Treatment of preterm birth and treatment of pregnancy-induced hypertension

The dosage and method were similar, and the initial loading was 4g. Diluted with 25% glucose injection 20ml, intravenous injection was given slowly within 5 minutes, followed by 25% magnesium sulfate injection 60ml, added to 5% glucose injection 1000ml intravenously, at a rate of 2g per hour, until 2 hours after contraction stopped, and then oral βadrenoreceptor agonists were maintained.

Matters needing attention:

1. Kidney function should be checked before the application of magnesium sulfate injection, such as renal insufficiency should be used with caution, the dosage should be reduced.

2. It should be used with or without caution when there is myocardial damage or heart block.

3. Before and during each medication, regular knee tendon reflexes should be performed to determine the number of breaths, observe urine volume, and draw blood to check the blood magnesium concentration value. If knee tendon reflexes are significantly weakened or disappeared, or the number of breaths is less than 14 to 16 times per minute, the urine volume is less than 25 to 30ml per hour or less than 600ml in 24 hours, the medication should be stopped in time.

4. The sudden occurrence of chest tightness, chest pain and shortness of breath during the course of medication should be timely auscultation, and chest X-ray film should be taken when necessary to detect pulmonary edema early.

5. If acute magnesium poisoning occurs, calcium injection can be used to rescue, commonly used 10% calcium gluconate injection 10ml slow injection.

6. During fetal preservation treatment, it is not appropriate to use with adrenergic β receptor agonists, such as ritodrine, otherwise it is easy to cause cardiovascular adverse reactions.