Cefepime Sodium for Injection 1g / High Quality

• Customization: Available
• Packaging From: 1+1/Box
• Packaging: Customization
• Model NO.: Powder for injection
• Dosage: Ready
• Certified: GMP
• Transport Package: Shipping
• Specification: 1g
• Trademark: Customization
• Origin: China
• Production Capacity: 10, 000, 000

Product Description

Value-added services:
 1) Packaging design by our team
 2) Registration service by our team
 3) Registration dossier available by our team
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Cefepime Sodium for Injection 1g

Composition:

Each vial contains:

• Cefepime Sodium - 1g (equivalent to 1g Cefepime base)

Description:

Cefepime is a fourth-generation cephalosporin antibiotic with a broad-spectrum activity against gram-positive and gram-negative bacteria, including Pseudomonas aeruginosa. It inhibits bacterial cell wall synthesis, making it effective for severe infections.

Indications:

Cefepime Sodium for Injection is used for the treatment of infections caused by susceptible organisms, including:

• Respiratory tract infections (pneumonia, bronchitis, nosocomial infections)
• Urinary tract infections (UTI, complicated & uncomplicated)
• Skin & soft tissue infections
• Intra-abdominal infections (in combination with metronidazole)
• Febrile neutropenia (empiric therapy in immunocompromised patients)
• Septicemia (bacteremia caused by susceptible organisms)
• Meningitis (caused by susceptible bacteria, including Streptococcus pneumoniae)

Dosage & Administration:

Intravenous (IV) or Intramuscular (IM) Use

Adults & Children > 12 years (≥ 40 kg):

• Mild to moderate infections: 1g every 12 hours
• Severe infections: 2g every 8-12 hours
• Febrile neutropenia or nosocomial pneumonia: 2g every 8 hours

Children (2 months to 12 years, < 40 kg):

• 50 mg/kg every 12 hours (mild to moderate infections)
• 50 mg/kg every 8 hours (severe infections)

Reconstitution & Administration:

• IV injection: Dissolve 1g vial in 10mL sterile water; administer over 3-5 minutes
• IV infusion: Further dilute in 50-100mL normal saline or 5% dextrose and infuse over 30 minutes
• IM injection: Dissolve 1g vial in 3mL sterile water or lidocaine 0.5% (for pain reduction)

Contraindications:

• Hypersensitivity to cefepime, cephalosporins, or β-lactam antibiotics
• History of severe allergic reactions (e.g., anaphylaxis, angioedema)

Precautions:

• Use with caution in patients with renal impairment (dose adjustment required)
• Monitor for Clostridium difficile-associated diarrhea (CDAD)
• Risk of neurotoxicity in renal failure patients (seizures, encephalopathy, confusion)

Adverse Reactions:

• Common: Nausea, vomiting, diarrhea, rash, pain at injection site
• Serious: Anaphylaxis, Clostridium difficile colitis, seizures, nephrotoxicity

Drug Interactions:

• Aminoglycosides & diuretics (e.g., furosemide): Increased risk of nephrotoxicity
• Probenecid: May reduce cefepime clearance
• Warfarin: May increase bleeding risk

Overdose & Management:

• Symptoms: Neurotoxicity (seizures, confusion, coma), renal dysfunction
• Treatment: Supportive care, hemodialysis if needed

Storage Conditions:

• Store below 25°C, protect from light and moisture
• Use reconstituted solution within 24 hours (if refrigerated) or 12 hours (at room temperature)