Cefalotin Sodium for Injection 1g / High Quality

• Customization: Available
• Packaging From: 10 Vials /Box
• Packaging: Customization
• Model NO.: Powder for injection
• Dosage: Ready
• Certified: GMP
• Transport Package: Shipping
• Specification: 1g
• Trademark: Customization
• Origin: China

Product Description

Value-added services:
 1) Packaging design by our team
 2) Registration service by our team
 3) Registration dossier available by our team
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Cefalotin Sodium for Injection 1g

Composition:

Each vial contains:

• Cefalotin Sodium equivalent to 1g of Cefalotin

Description:

Cefalotin Sodium is a first-generation cephalosporin antibiotic with bactericidal activity. It works by inhibiting bacterial cell wall synthesis, making it effective against Gram-positive and some Gram-negative bacteria.

Indications:

Cefalotin Sodium for Injection is indicated for the treatment of infections caused by susceptible organisms, including:

• Respiratory tract infections (pneumonia, bronchitis)
• Skin and soft tissue infections
• Urinary tract infections
• Bone and joint infections
• Septicemia and endocarditis
• Prophylaxis in surgical procedures

Dosage & Administration:

Intravenous (IV) or Intramuscular (IM) Use

Adults:

• Mild to moderate infections: 500mg to 1g IV/IM every 6-8 hours
• Severe infections: 2g IV every 4-6 hours
• Surgical prophylaxis: 1-2g IV 30 minutes before surgery, followed by 1-2g every 6-8 hours for 24 hours

Pediatrics:

• Usual dose: 50-100mg/kg/day IV/IM in divided doses every 6-8 hours
• Severe infections: Up to 150mg/kg/day

Preparation & Administration:

• For IM injection: Dissolve 1g vial in 4mL sterile water for injection
• For IV injection: Dissolve 1g vial in 10mL sterile water for injection, inject slowly over 3-5 minutes
• For IV infusion: Dilute 1g in 50-100mL of 0.9% NaCl or 5% dextrose, infuse over 30-60 minutes
• Do not mix with aminoglycosides in the same syringe or IV line

Contraindications:

• Hypersensitivity to cephalosporins or beta-lactam antibiotics

Precautions:

• Use with caution in renal impairment (adjust dose accordingly)
• Monitor for hypersensitivity reactions (cross-reactivity with penicillin possible)
• Prolonged use may lead to superinfection (e.g., Clostridium difficile colitis)

Adverse Reactions:

• Common: Nausea, vomiting, diarrhea, rash, pain at injection site
• Serious: Hypersensitivity reactions, anaphylaxis, nephrotoxicity, pseudomembranous colitis

Drug Interactions:

• Increased nephrotoxicity risk with aminoglycosides or loop diuretics
• May enhance anticoagulant effects of warfarin (monitor INR closely)

Overdose & Management:

• Symptoms: Seizures, nephrotoxicity
• Treatment: Supportive care, hemodialysis may be beneficial

Storage Conditions:

• Store below 25°C, protect from light
• Use reconstituted solution within 6 hours (room temperature) or 24 hours (refrigerated at 2-8°C)