Customization: | Available |
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Dosage Form: | Injection |
Dossier: | Ready |
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Generic Name | Cimetidine Injection 200mg/2ml |
Strength | 200mg/2ml |
Packing | 10ampoules/box |
Origin | China |
This product is a colorless clear liquid.
For digestive tract ulcers.
Usage and dosage:
Intravenous infusion: 0.2g of this product is diluted with 5% glucose injection or 0.9% sodium oxide injection or glucose sodium chloride injection 250-500ml before intravenous infusion at a rate of L-4mg /kg per hour, 0.2-0.6g each time. Intravenous injection: Dilute 20ml with the above solution and slowly inject intravenously (2-3 minutes), once every 6 hours, 0.2g each time. Intramuscular injection: 0.2g once, once every 6 hours.
Matters needing attention:
1. Digestive system reaction. More common diarrhea, abdominal distension, dry mouth, slightly elevated serum aminotransferase, occasionally severe hepatitis, liver damage, liver steatosis, etc. Acute pancreatitis has been reported both in animal experiments and in clinic. Sudden discontinuation may lead to chronic peptic ejaculation and perforation.
2. Urinary system reaction. There have been reports of acute interstitial nephritis leading to scorpion decay, but this toxic effect is reversible.
3. Hematopoietic system reaction. It has a certain inhibitory effect on bones. A few patients developed reversible moderate leukopenia or granulocytosis.
4. Central nervous system response. It can have certain neurotoxicity through blood and brain. More common are dizziness, headache, fatigue, lethargy and so on. After neurotoxicity occurs, it usually disappears by reducing the dose appropriately, and the symptoms can be improved by treating with physostigine, a quasi-cholinergic drug.
5. Cardiovascular system reactions may include bradycardia, facial flushing, etc. Occasionally, sudden drop of blood pressure, premature atrial beat, cardiac and respiratory arrest, shortness of breath or difficulty breathing were observed during intravenous injection.
6. On endocrine and skin effects, this drug has anti-male stimulant effect. When the dosage is large, it can cause male breast development, female galactorrhea, decreased sexual desire, positive fistula, reduced sperm count, etc., which can disappear after stopping the drug; It can inhibit sebum secretion, induce exfoliative dermatitis, alopecia, oral ulcer and so on.