| Customization: | Available |
|---|---|
| Quality Standard: | USP, Bp |
| Package: | 30 Tablets |
|
Still deciding? Get samples of US$ 0.01/Piece
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
| Generic Name |
Paracetamol Tablets |
| Strength | 500mg |
| Packing | 30 tablets/box |
| Origin | China |
Value-added services:
Packaging design by our team
Registration service by our team
Registration dossier available by our team
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Product name:
Paracetamol Tablets 500mg
Character:
This product is white.
Indications:
The main ingredient is acetaminophen, the metabolite of phenacetin in the body, which belongs to the aniline class. This product is absorbed rapidly and completely by mouth, and most of it is metabolized in the liver with a half-life of 1-4 hours. Clinically used for cold fever, joint pain, neuralgia, migraine treatment.
Drug interaction:
(1) In long-term alcohol consumption or use of other liver enzyme inducers, especially in patients using barbiturates or anticonvulsants, long-term or large doses of this product, there is a greater risk of liver toxicity.
(2) The combination of this product with chloramphenicol can prolong the half-life of the latter and enhance its toxicity.
(3) Combined with anticoagulants can enhance the anticoagulant effect, so it is necessary to adjust the dosage of anticoagulants. (4) Long-term use with aspirin or other non-steroidal anti-inflammatory drugs, there is a significant increase in the risk of renal toxicity.
(5) When combined with antiviral Zidovudine, it can increase its toxicity and should be avoided at the same time.
Pharmacology and toxicology:
This product is acetanilide antipyretic analgesic. By inhibiting cyclooxygenase, selective inhibition of prostaglandin synthesis in hypothalamic thermoregulatory center leads to peripheral vascular dilation and sweating, thus achieving antipyretic effect, which is similar to aspirin. It plays an analgesic role by inhibiting the synthesis and release of prostaglandins, etc. and raising the pain threshold. It is a peripheral analgesic drug with a weaker effect than aspirin and is only effective for light and moderate pain. This product has no obvious anti-inflammatory effect.
Pharmacokinetics This product is absorbed rapidly and completely after oral administration, and distributes evenly in the body after absorption. The blood concentration reached the peak 0.5 ~ 2 hours after oral administration. The plasma protein binding rate is about 25% ~ 50%. 90% ~ 95% of this product is metabolized in the liver, and the main metabolites are glucuronic acid and sulfuric acid conjugates. It is mainly excreted from the kidneys in the form of binding with glucuronic acid, and about 3% is excreted in urine in its original form within 24 hours. Its plasma half-life is l ~ 3 hours, the half-life of renal insufficiency is not affected, but the half-life of patients with liver dysfunction, neonates and the elderly is prolonged, and the half-life of children is shortened. It can be secreted by milk.
Storage:
Keep in airtight storage.
){kind=link}