Esomeprazole is a proton pump inhibitor, and a type of medication used to treat symptoms of gastroesophageal reflux disease (GERD) and other diseases involving excess stomach acid. It helps to lower the quantity of acid generated in the stomach. Following therapy, it is used to treat acid-related disorders of the stomach and intestine such as acid reflux, peptic ulcer disease, and duodenal ulcers following therapeutic Endoscopy and frequent heartburn. Esomeprazole Injection is also used to avoid stress ulcers in critically ill patients, and it is given before anaesthesia medicine to assist prevent aspiration problems.
Precautions For Esomeprazole Injection
A healthcare practitioner will deliver Esomeprazole Injection into a vein if the doctor believes that an injection is more appropriate for the patient at this time than a tablet. Inform the doctor if the patient has had any kidney issue or taking the medication of treating hypertension. Do not take this injection by yourself at home.
Side Effects Of Esomeprazole Injections
Esomeprazole Injection has some side effects which need to be kept in mind before starting this medicine. If the patient faces any serious side effects then visit the doctor immediately.
· Flatulence
· Headache
· Nausea
· Constipation
· Diarrhea
· Dizziness
· Dryness in mouth
· Injection site reaction
· Drug Interactions
Esomeprazole is a competitive inhibitor of the enzyme CYP2C19, and may therefore interact with drugs that depend on it for metabolism, such as diazepam and warfarin, the concentrations of these drugs may increase if they are used concomitantly with esomeprazole. Conversely, clopidogrel is an inactive prodrug that partially depends on CYP2C19 for conversion to its active form, inhibition of CYP2C19 blocks the activation of clopidogrel, thus reducing its effects. Drugs that depend on stomach pH for absorption may interact with omeprazole, drugs that depend on an acidic environment will be poorly absorbed, whereas drugs that are broken down in acidic environments will be absorbed to a greater extent than normal.
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