Nicardipine Hydrochloride Injection 10mg / High Quality

• Customization: Available
• Packaging From: 10 Ampoules/Box
• Packaging: Customization
• Model NO.: injection
• Dosage: Ready
• Transport Package: Shipping
• Specification: 10mg
• Trademark: brand
• Origin: China

Product Description

Value-added services:
 1) Packaging design by our team
 2) Registration service by our team
 3) Registration dossier available by our team
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Nicardipine Hydrochloride Injection 10mg

Composition:

Each (X ml) contains:

• Nicardipine Hydrochloride .........… 10mg
• Excipients .........… (as required)

Description:

Nicardipine Hydrochloride is a calcium channel blocker (CCB) of the dihydropyridine class, primarily used for blood pressure control by relaxing vascular smooth muscle and reducing systemic vascular resistance.

Indications:

Nicardipine Injection is indicated for:

• Hypertensive emergencies
• Perioperative hypertension management
• Acute stroke-related blood pressure control
• Postoperative blood pressure management

Dosage & Administration:

Intravenous Administration Only

• Initial infusion rate: 5 mg/hour, titrated up every 15 minutes by 2.5 mg/hour as needed
• Maximum infusion rate: 15 mg/hour
• Maintenance dose: 3-5 mg/hour once blood pressure is controlled
• Duration: Short-term use, transition to oral antihypertensive as soon as possible

Contraindications:

• Hypersensitivity to Nicardipine or dihydropyridine CCBs
• Severe aortic stenosis (may worsen hemodynamics)
• Severe hypotension or cardiogenic shock
• Acute decompensated heart failure

Precautions:

• Monitor blood pressure continuously during infusion
• Use cautiously in renal and hepatic impairment
• Avoid abrupt discontinuation to prevent rebound hypertension
• Caution in patients with ischemic heart disease (may cause reflex tachycardia)

Adverse Reactions:

• Common: Hypotension, flushing, dizziness, headache, nausea
• Serious: Reflex tachycardia, arrhythmia, pulmonary edema, hepatotoxicity

Drug Interactions:

• Enhanced hypotensive effect with other antihypertensives (e.g. ACE inhibitors)
• Avoid concomitant use with strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
• May interact with anesthetic agents in perioperative settings

Overdose & Management:

• Symptoms: Severe hypotension, bradycardia, syncope, dizziness
• Treatment: Stop infusion, administer IV fluids, vasopressors if needed, and monitor ECG

Storage Conditions:

• Store at 20-25°C, protect from light
• Do not freeze