GMP Certified / Potassium Chloride Sustained Release Tablets.

• Quality Standard: Bp, USP
• Ctd Dossier: Ready
• Documentation: Copp, COA
• Factory Certification: GMP
• Transport Package: Carton
• Specification: 600mg
• Model NO.: Tablet
• Trademark: Sinolead
• Origin: China
• Production Capacity: 100, 000, 000 Per Year

Product Description

Product Description

Generic Name	Potassium Chloride Sustained-release Tablets
Strength	600 mg
Packing	100 tablets /bottle
Origin	China

Value-added services:
 Packaging design by our team
 Registration service by our team
 Registration dossier available by our team
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Product name:
Potassium Chloride Sustained-release Tablets

Character:
This product is sugar-coated tablet, after removing the coating will appear white.

Indications:
1. Treatment of hypokalemia caused by various causes, such as insufficient eating, vomiting, severe diarrhea, application of potassium diuretic drugs, hypokalemic familial periodic paralysis, long-term use of glucocorticoids and hypertonic glucose supplement.
2. Prevention of hypokalemia When patients have potassium loss, especially if the occurrence of hypokalemia is harmful to patients (such as patients with digitalization), preventive potassium salt supplementation is required, such as eating little, severe or chronic diarrhea, long-term use of suprrenal gland corticosteroids, potassium loss nephropathy, and Bartte's syndrome.
3. Digitalis poisoning causes frequent, multigenic premature beats or tachyarrhythmias.

Matters needing attention:
This product should be swallowed, do not bite. Use with caution in the following cases:
1. Metabolic acidosis accompanied by oliguria;
2. Patients with weakened adrenal cortex function;
3. Acute and chronic renal failure;
4. Acute dehydration, which can cause reduced urine volume and reduced urine K+ excretion when it is severe;
5. Familial periodic paralysis; Hypokalemic paralysis should be supplemented with potassium, but it is necessary to distinguish between hyperkalemic paralysis and normal kalemic periodic paralysis.
6. Chronic or severe diarrhea can cause hypokalemia, but it can also cause dehydration and hyponatremia, causing prerenal oliguria;
7. Gastrointestinal obstruction, chronic gastritis, ulcer disease, esophageal stenosis, diverticulum, intestinal tension deficiency, and ulcerative enteritis, it is not appropriate to oral potassium supplementation, so potassium stimulation of the gastrointestinal tract increases, which can aggravate the condition;
8. Blocking arrhythmia, especially when digitalis is used;
9. Large-scale burns, muscle trauma, severe infection, severe hemolysis within 24 hours after major surgery, which can cause hyperkalemia by itself;
10. Congenital adrenal hyperplasia with insufficient secretion of corticosteroids.
11. The following follow-up examinations should be performed during the medication period;
(1) blood potassium;
(2) electrocardiogram;
(3) Blood magnesium, sodium, calcium;
(4) acid-base balance index;
(5) Renal function and urine volume.

Pharmacology and toxicology:
Potassium is the main intracellular cation, and its concentration is 150-160 mmol/L. The main cation outside the cell is sodium ion, and the concentration of potassium is only 3.5-5mmol /Lo. The body mainly relies on Na+-K± ATPase on the cell membrane to maintain the concentration difference of K+ and Na+ in the cell. The acid-base balance in the body has an impact on potassium metabolism, such as acidosis when H+ enters the human cell, in order to maintain the potential difference of the cell, K+ is released outside the cell, causing or aggravating hyperkalemia. Metabolic disorders can also affect acid-base balance. Normal intracellular and intracellular potassium ion concentration and concentration difference are closely related to some important cellular functions, including the maintenance of carbohydrate metabolism, glycogen storage, protein metabolism, intracellular osmotic pressure and acid-base balance, myocardial excitability and conductivity. Maintain the normal skeletal muscle tension and nerve impulse conduction, and can make the intestinal, uterine and bronchial muscle tension rise.


Storage:
Seal and store in a dry place.