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| Materials: | PP/Glass |
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Hydroxyethyl Starch (HES) 130/0.4 and Sodium Chloride Injection is a sterile, non-pyrogenic solution designed for intravenous administration. It is a plasma volume expander used to restore and maintain circulating blood volume in patients with hypovolemia.
Active Ingredients:
Hydroxyethyl Starch 130/0.4: A synthetic colloid derived from waxy maize starch.
Sodium Chloride: An electrolyte solution for maintaining osmotic balance.
Concentration: Typically available in 6% HES 130/0.4 in 0.9% sodium chloride.
Formulation: Clear, slightly viscous solution.
Administration: Intravenous infusion.
Packaging: Single-dose bags or bottles, commonly in 250ml, 500ml, or 1000ml sizes.
Hypovolemia: Treatment and prevention of hypovolemia due to acute blood loss, surgery, or trauma.
Plasma Volume Expansion: Used as a plasma substitute to maintain hemodynamic stability in critically ill patients.
Electrolyte Balance: Helps restore and maintain electrolyte and fluid balance.
Hydroxyethyl Starch: Acts as a colloid osmotic agent, drawing fluid into the intravascular space to increase plasma volume.
Sodium Chloride: Provides essential electrolytes to maintain osmotic pressure and fluid balance.
Recommended Dosage:
Adults: Typically 500-1000 ml per day, depending on the patient's condition and hemodynamic response.
Maximum Daily Dose: Usually limited to 50 ml/kg body weight to avoid adverse effects.
Administration: Administered intravenously, either as a bolus or continuous infusion, depending on the clinical situation.
Infusion Rate: Adjusted based on the patient's hemodynamic status and response.
Effective Plasma Expansion: Provides rapid and sustained plasma volume expansion.
Hemodynamic Stability: Helps maintain blood pressure and perfusion in critically ill patients.
Safety Profile: Lower risk of anaphylactoid reactions compared to some other colloids.
Storage: Store at controlled room temperature (15-30°C). Protect from freezing and excessive heat.
Shelf Life: Typically 24-36 months, depending on the manufacturer.
Contraindicated in patients with severe renal impairment, intracranial bleeding, or known hypersensitivity to hydroxyethyl starch.
Use with caution in patients with heart failure, severe liver disease, or coagulation disorders.
Monitor renal function, fluid balance, and coagulation parameters during treatment.
Common side effects include itching, mild allergic reactions, and fluid overload.
Rare but serious side effects may include renal impairment, coagulopathy, and anaphylaxis.
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