Moxifloxacin Hydrochloride and Sodium Chloride Injection 250ml: 400mg / High Quality

• Customization: Available
• Packing: Customization
• Materials: PP/Glass
• Model NO.: injection
• Transport Package: Carton
• Specification: 250ml: 400mg
• Trademark: Sinolead
• Origin: China

Product Description

Value-added services:
 Packaging design by our team
 Registration service by our team
 Registration dossier available by our team
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Moxifloxacin Hydrochloride and Sodium Chloride Injection 250ml: 400mg

Product Overview

Moxifloxacin Hydrochloride and Sodium Chloride Injection is a sterile, non-pyrogenic solution designed for intravenous administration. It contains 400mg of Moxifloxacin Hydrochloride (a broad-spectrum fluoroquinolone antibiotic) in 250ml of 0.9% Sodium Chloride solution, providing a ready-to-use formulation for the treatment of bacterial infections.

Key Features

• Active Ingredient: Moxifloxacin Hydrochloride

• Concentration: 400mg/250ml (1.6mg/ml)

• Formulation: Clear, slightly yellow to yellow solution

• Administration: Intravenous infusion

• Packaging: Single-dose bag or bottle, 250ml per unit

Indications

• Bacterial Infections: Treatment of adults with infections caused by susceptible strains of bacteria, including:

  • Community-acquired pneumonia (CAP)

  • Acute bacterial sinusitis (ABS)

  • Complicated skin and skin structure infections (cSSSI)

  • Complicated intra-abdominal infections (cIAI)

• Broad-Spectrum Activity: Effective against Gram-positive, Gram-negative, anaerobic, and atypical pathogens.

Mechanism of Action

• Moxifloxacin is a fourth-generation fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication, transcription, and repair.

• This action leads to bacterial cell death and prevents further growth of susceptible organisms.

Dosage and Administration

• Recommended Dosage:

  • Adults: 400mg (250ml) once daily, administered intravenously.

  • Duration of Treatment: Typically 7-14 days, depending on the type and severity of the infection.

• Administration:

  • Must be administered as a slow intravenous infusion over 60-90 minutes.

  • Can be switched to oral moxifloxacin (400mg once daily) once the patient's condition improves.

• Compatibility: Can be infused with other compatible intravenous fluids if needed.

Advantages

• Broad-Spectrum Coverage: Effective against a wide range of bacterial pathogens.

• Once-Daily Dosing: Convenient dosing regimen improves patient compliance.

• Ready-to-Use Formulation: Eliminates the need for reconstitution, reducing preparation time and risk of errors.

Storage and Handling

• Storage: Store at controlled room temperature (15-30°C). Protect from light and freezing.

• Shelf Life: Typically 24-36 months, depending on the manufacturer.

Precautions

• Contraindicated in patients with known hypersensitivity to moxifloxacin, other fluoroquinolones, or any component of the formulation.

• Use with caution in patients with:

  • Prolonged QT interval or risk of arrhythmias.

  • Tendon disorders or risk of tendon rupture.

  • Central nervous system disorders (e.g., epilepsy).

• Avoid use in pregnant or lactating women unless absolutely necessary.

Adverse Effects

• Common side effects include nausea, diarrhea, dizziness, and headache.

• Rare but serious side effects may include:

  • Tendon rupture.

  • Peripheral neuropathy.

  • QT prolongation and arrhythmias.

  • Severe hypersensitivity reactions.