Cefixime Capsule 400mg / High Quality

• Customization: Available
• Certified: GMP
• Dossier: Ctd
• Model NO.: capsule
• Packing: Customization
• Package: 6 Capsules / Box
• Transport Package: Box
• Specification: 400mg
• Trademark: Sinolead
• Origin: China

Product Description

Cefixime Capsules 400mg

Composition:

Each capsule contains:

• Cefixime (as Cefixime Trihydrate) 400mg

Description:

Cefixime is a third-generation cephalosporin antibiotic with broad-spectrum activity against Gram-positive and Gram-negative bacteria. It is commonly used for the treatment of various bacterial infections, particularly those affecting the respiratory and urinary tracts.

Indications:

Cefixime Capsules 400mg are indicated for the treatment of infections caused by susceptible bacteria, including:

• Respiratory tract infections (pharyngitis, tonsillitis, bronchitis)
• Urinary tract infections (UTIs), including cystitis and pyelonephritis
• Uncomplicated gonorrhea (Neisseria gonorrhoeae)
• Otitis media (middle ear infection)
• Sinusitis
• Typhoid fever (caused by Salmonella typhi)

Dosage & Administration:

• Adults & Adolescents (≥12 years or ≥45 kg):
  • 400mg once daily OR 200mg every 12 hours
  • Duration:
    • Respiratory and urinary tract infections: 7-14 days
    • Gonorrhea: Single 400mg dose
    • Typhoid fever: 10-14 days
• Children (6 months - 12 years):
  • 8 mg/kg/day as a single dose OR 4 mg/kg every 12 hours
• Renal Impairment:
  • Dose adjustment required if creatinine clearance <60 mL/min

Administration:

• Can be taken with or without food.
• Swallow the capsule whole with water.

Contraindications:

• Hypersensitivity to Cefixime, cephalosporins, or penicillins.

Precautions:

• Use with caution in patients with renal impairment.
• Monitor for Clostridium difficile-associated diarrhea.
• May cause false-positive urine glucose test in diabetic patients.

Adverse Reactions:

• Gastrointestinal: Nausea, vomiting, diarrhea, abdominal pain.
• Allergic Reactions: Rash, urticaria, anaphylaxis (rare).
• Hematologic: Leukopenia, thrombocytopenia.
• Hepatic: Elevated liver enzymes (ALT, AST).

Drug Interactions:

• Probenecid may increase cefixime levels.
• May enhance anticoagulant effects of warfarin.
• May interfere with oral contraceptives.

Storage Conditions:

• Store below 25°C, protect from light and moisture.
• Keep out of reach of children.