Propofol Injectable Emulsion 100mg/10ml / High Quality

• Customization: Available
• Packaging From: 5 Ampoules/Box
• Packaging: Customization
• Model NO.: injection
• Dosage: Ready
• Transport Package: Shipping
• Specification: 10ml: 100mg
• Trademark: brand
• Origin: China

Product Description

Value-added services:
 1) Packaging design by our team
 2) Registration service by our team
 3) Registration dossier available by our team
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------

Propofol Injectable Emulsion 100mg/10mL

Composition:

Each 10mL ampoule contains:

• Propofol - 100mg (10mg/mL)
• Excipients: Soya bean oil, Glycerol, Egg lecithin, Sodium hydroxide (for pH adjustment), Water for injection

Description:

Propofol is a short-acting intravenous anesthetic used for induction and maintenance of general anesthesia and sedation. It provides rapid onset and smooth recovery, making it ideal for surgical and intensive care use.

Indications:

• Induction and maintenance of general anesthesia
• Sedation of mechanically ventilated patients in intensive care units (ICU)
• Procedural sedation for diagnostic and therapeutic procedures

Dosage & Administration:

Induction of General Anesthesia:

• Adults: 1.5-2.5 mg/kg IV bolus over 20-30 seconds
• Elderly & debilitated patients: Lower initial dose (1-1.5 mg/kg)

Maintenance of General Anesthesia:

• Continuous IV infusion: 4-12 mg/kg/hour

Sedation in ICU (Ventilated Patients):

• Initial dose: 0.3-4 mg/kg/hour IV infusion
• Titration: Adjust based on response

Procedural Sedation:

• Initial bolus: 0.5-1 mg/kg IV
• Maintenance infusion: 1.5-4.5 mg/kg/hour

Administration:

• IV use only
• Avoid rapid bolus administration in elderly patients
• Shake well before use

Contraindications:

• Hypersensitivity to propofol, soybean oil, or egg lecithin
• Patients with severe cardiac or respiratory compromise
• Pediatric sedation in intensive care (not recommended for prolonged use in children under 16 years)

Precautions:

• Monitor oxygenation, ventilation, and circulation continuously
• Caution in patients with hypotension, hypovolemia, or lipid metabolism disorders
• Risk of Propofol Infusion Syndrome (PRIS) with prolonged use in ICU

Adverse Reactions:

• Common: Hypotension, bradycardia, apnea, injection site pain
• Serious: Respiratory depression, metabolic acidosis, PRIS (in rare cases)

Drug Interactions:

• CNS depressants (opioids, benzodiazepines): Enhanced sedative effects
• Muscle relaxants: May increase neuromuscular blockade
• Alcohol and anesthetics: Additive CNS depression

Overdose & Management:

• Symptoms: Severe hypotension, respiratory depression, cardiovascular collapse
• Treatment: Discontinue propofol, provide airway support, oxygen, fluids, vasopressors if needed

Storage Conditions:

• Store between 2°C-25°C
• Do not freeze
• Use within 6 hours of opening