Cefazolin Sodium for Injection 500mg / High Quality

• Customization: Available
• Packaging From: 10 Vials /Box
• Packaging: Customization
• Model NO.: Powder for injection
• Dosage: Ready
• Certified: GMP
• Transport Package: Shipping
• Specification: 500mg
• Trademark: Customization
• Origin: China
• Production Capacity: 10000000

Product Description

Value-added services:
 1) Packaging design by our team
 2) Registration service by our team
 3) Registration dossier available by our team
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Cefazolin Sodium for Injection 500mg

Composition:

Each vial contains:

• Cefazolin Sodium equivalent to Cefazolin 500mg

Description:

Cefazolin is a first-generation cephalosporin antibiotic with broad-spectrum activity against Gram-positive and some Gram-negative bacteria. It is widely used for the treatment of various bacterial infections and for perioperative prophylaxis to prevent postoperative infections.

Indications:

Cefazolin Sodium for Injection is indicated for the treatment of infections caused by susceptible bacteria, including:

• Respiratory tract infections (pneumonia, bronchitis)
• Urinary tract infections (UTIs)
• Skin and soft tissue infections (cellulitis, abscesses)
• Bone and joint infections (osteomyelitis, septic arthritis)
• Septicemia (bacteremia)
• Endocarditis
• Gynecological infections (postpartum infections)
• Perioperative prophylaxis (to prevent surgical infections)

Dosage & Administration:

• Adults:
  • 500mg-1g every 6-12 hours via intravenous (IV) or intramuscular (IM) injection
  • Maximum dose: 6g per day
• Children:
  • 25-50 mg/kg/day in divided doses every 8 hours
  • In severe infections, the dose may be increased to 100 mg/kg/day
• Surgical Prophylaxis:
  • 1g IV injection 30-60 minutes before surgery, with additional doses if needed postoperatively.
• Patients with Renal Impairment:
  • Dosage adjustment is required for creatinine clearance ≤30 mL/min.

Administration:

• Intramuscular (IM): Reconstitute with sterile water for injection or lidocaine solution (if recommended).
• Intravenous (IV): Reconstitute with sterile water for injection and administer as a slow IV injection (3-5 minutes) or IV infusion over 30-60 minutes.

Contraindications:

• Hypersensitivity to Cefazolin, cephalosporins, or penicillins.

Precautions:

• Perform a skin sensitivity test before administration in allergic patients.
• Use with caution in renal impairment; dose adjustments may be required.
• Monitor for gastrointestinal side effects, such as diarrhea or pseudomembranous colitis.

Adverse Reactions:

• Gastrointestinal: Nausea, vomiting, diarrhea, abdominal pain.
• Allergic Reactions: Rash, pruritus, anaphylaxis (rare).
• Hematologic: Leukopenia, thrombocytopenia, eosinophilia.
• Hepatic: Transient increase in liver enzymes (AST, ALT).

Drug Interactions:

• May enhance the nephrotoxicity of aminoglycosides and loop diuretics.
• May interfere with glucose urine tests, leading to false-positive results.

Storage Conditions:

• Store below 25°C, protect from light and moisture.
• Keep out of reach of children.