Diclofenac Sodium Injection 3ml: 75mg / High Quality

• Customization: Available
• Packaging From: 10 Ampoules/Box
• Packaging: Customization
• Model NO.: injection
• Dosage: Ready
• Transport Package: Shipping
• Specification: 3ml: 75mg
• Trademark: brand
• Origin: China

Product Description

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Diclofenac Sodium Injection 3ml: 75mg

Composition:

Each 3ml ampoule contains:

• Diclofenac Sodium 75mg

Description:

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) with potent analgesic, anti-inflammatory, and antipyretic properties. It works by inhibiting cyclooxygenase (COX-1 and COX-2), reducing prostaglandin synthesis, which is responsible for pain and inflammation.

Indications:

Diclofenac Sodium Injection is used for the short-term treatment of acute pain and inflammation, including:

• Postoperative pain
• Severe musculoskeletal pain (e.g., back pain, sprains, and fractures)
• Renal colic and biliary colic
• Acute gout attacks
• Pain and inflammation due to rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis

Dosage & Administration:

Adults:

• Single dose: 75mg (1 ampoule) once daily via IM injection
• If needed, a second dose of 75mg can be given after 6-12 hours
• Maximum daily dose: 150mg (2 ampoules) per day
• Duration of treatment: Use for the shortest possible duration (usually 2-3 days). If needed, switch to oral or rectal Diclofenac for continued therapy.

Elderly Patients:

• Use the lowest effective dose due to increased risk of gastrointestinal and cardiovascular side effects.

Patients with Hepatic or Renal Impairment:

• Use with caution-dose adjustments may be needed.
• Severe renal or hepatic impairment: Use is not recommended.

Administration:

• Administer by deep intramuscular (IM) injection into the gluteal muscle.
• Do not inject intravenously (IV) or subcutaneously.
• Rotate injection sites to prevent muscle irritation.

Contraindications:

• Hypersensitivity to Diclofenac, other NSAIDs, or excipients
• Active peptic ulcer, gastrointestinal bleeding, or perforation
• Severe hepatic or renal impairment
• Severe heart failure
• Patients with a history of NSAID-induced asthma, urticaria, or angioedema
• Pregnancy (third trimester)

Precautions:

• Cardiovascular Risk: Long-term use may increase the risk of heart attack, stroke, and hypertension.
• Gastrointestinal Risk: Risk of gastric ulcers, bleeding, and perforation-use with caution in patients with a history of ulcers or gastrointestinal disease.
• Renal Effects: May cause fluid retention, hypertension, and kidney dysfunction-monitor renal function, especially in high-risk patients.
• Liver Toxicity: Monitor liver enzymes with prolonged use.
• Avoid Concomitant NSAIDs: Increases the risk of side effects.

Adverse Reactions:

• Common: Pain at the injection site, nausea, vomiting, dizziness, headache
• Serious: Gastrointestinal bleeding, hypertension, liver toxicity, kidney dysfunction, allergic reactions (rash, anaphylaxis)

Drug Interactions:

• Anticoagulants (Warfarin, Heparin): Increased bleeding risk
• Diuretics & ACE Inhibitors: May reduce effectiveness-monitor renal function
• Corticosteroids & Other NSAIDs: Increased risk of gastrointestinal bleeding
• Lithium & Methotrexate: May increase toxicity levels-monitor closely

Storage Conditions:

• Store below 25°C, in a dry place
• Protect from light and moisture