Acyclovir Capsules 200mg / High Quality

• Customization: Available
• Certified: GMP
• Dossier: Ctd
• Model NO.: capsule
• Packing: Customization
• Package: 100 Capsules / Box
• Transport Package: Box
• Specification: 200mg
• Trademark: Sinolead
• Origin: China

Product Description

Acyclovir Capsules 200mg

Composition:

Each capsule contains:

• Acyclovir 200 mg

Description:

Acyclovir is an antiviral agent that belongs to the class of nucleoside analogs. It inhibits herpes simplex virus (HSV) DNA polymerase, preventing viral replication. It is effective against Herpes Simplex Virus Type 1 (HSV-1), Herpes Simplex Virus Type 2 (HSV-2), and Varicella-Zoster Virus (VZV).

Indications:

Acyclovir Capsules are indicated for the treatment of:

• Herpes Simplex Virus (HSV) infections, including genital herpes
• Recurrent herpes simplex infections (suppression therapy)
• Varicella (chickenpox) and herpes zoster (shingles)
• Prevention of herpes simplex infections in immunocompromised patients

Dosage & Administration:

Adults:

• Herpes simplex (initial infection): 200 mg every 4 hours (5 times daily) for 5-10 days
• Recurrent herpes simplex (suppression therapy): 400 mg twice daily for up to 12 months
• Varicella (chickenpox): 800 mg 5 times daily for 5-7 days
• Herpes zoster (shingles): 800 mg every 4 hours (5 times daily) for 7-10 days

Pediatric Patients:

• Varicella (chickenpox):
  • 2-12 years: 20 mg/kg (max 800 mg per dose) 4 times daily for 5 days

Renal Impairment:

• CrCl < 10 mL/min: Reduce dose to 200 mg every 12 hours

Administration:

• Take orally with or without food
• Drink plenty of water to prevent kidney toxicity

Contraindications:

• Hypersensitivity to acyclovir or valacyclovir
• Severe renal impairment (use with caution, adjust dose)

Precautions:

• Renal toxicity risk in dehydrated or elderly patients-ensure adequate hydration
• Neurological side effects (agitation, hallucinations) possible in elderly patients
• Use with caution in immunocompromised patients-resistance may develop

Adverse Reactions:

• Common: Nausea, headache, dizziness, abdominal pain
• Serious: Acute kidney injury (rare), neurological symptoms (hallucinations, seizures)

Drug Interactions:

• Probenecid: Increases acyclovir levels-monitor for toxicity
• Mycophenolate mofetil: May increase acyclovir levels
• Theophylline: Acyclovir may increase its levels-monitor closely

Overdose & Management:

• Symptoms: Kidney failure, neurological toxicity (confusion, agitation, seizures)
• Treatment: Hydration, symptomatic management, hemodialysis if severe

Storage Conditions:

• Store below 25°C, protect from light and moisture
• Keep out of reach of children