Caspofungin Acetate for Injection 50mg / High Quality

• Customization: Available
• Packaging From: 1 Vial /Box
• Packaging: Customization
• Model NO.: Powder for injection
• Dosage: Ready
• Certified: GMP
• Transport Package: Shipping
• Specification: 50mg
• Trademark: Customization
• Origin: China

Product Description

Value-added services:
 1) Packaging design by our team
 2) Registration service by our team
 3) Registration dossier available by our team
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Caspofungin Acetate for Injection 50mg

Composition:

Each vial contains:

• Caspofungin Acetate equivalent to 50mg of Caspofungin

Description:

Caspofungin Acetate is an echinocandin antifungal that inhibits β-(1,3)-D-glucan synthase, an enzyme essential for fungal cell wall synthesis. It is effective against Candida and Aspergillus species.

Indications:

Caspofungin Acetate for Injection is indicated for:

• Invasive candidiasis, including candidemia
• Invasive aspergillosis (refractory to other antifungals)
• Empirical therapy for febrile neutropenia in suspected fungal infections

Dosage & Administration:

Intravenous (IV) Use Only

Administer via slow IV infusion over 1 hour.

Adult Dosage:

• Empirical therapy (febrile neutropenia): 70mg IV on Day 1, followed by 50mg IV daily
• Invasive candidiasis: Loading dose 70mg IV, then 50mg IV daily
• Invasive aspergillosis (salvage therapy): 70mg IV on Day 1, followed by 50mg IV daily

Pediatric Dosage (≥3 months old):

• Loading dose: 70mg/m² IV on Day 1
• Maintenance dose: 50mg/m² IV daily

Preparation & Administration:

• Reconstitute each 50mg vial with 10mL sterile water for injection (final concentration 5mg/mL)
• Further dilute in normal saline (0.9% NaCl) or 5% dextrose
• Administer via slow IV infusion over 1 hour
• Do not mix or infuse with other medications

Contraindications:

• Hypersensitivity to Caspofungin or any echinocandin antifungals

Precautions:

• Monitor liver function (dose adjustments in hepatic impairment)
• Caution in renal impairment
• Not recommended in pregnancy unless necessary

Adverse Reactions:

• Common: Fever, headache, nausea, rash
• Serious: Hepatotoxicity, hypersensitivity reactions, infusion-related reactions

Drug Interactions:

• Reduced efficacy with rifampin, efavirenz, phenytoin
• Monitor liver enzymes when used with cyclosporine

Overdose & Management:

• Symptoms: Liver enzyme elevation, infusion-related reactions
• Treatment: Supportive care, no specific antidote

Storage Conditions:

• Store below 25°C, protect from light
• Use reconstituted solution within 24 hours (if refrigerated at 2-8°C)