Amikacin Injection 500mg: 2ml / High Quality

• Customization: Available
• Packaging From: 1 Vial /Box
• Packaging: Customization
• Model NO.: Powder for injection
• Dosage: Ready
• Certified: GMP
• Transport Package: Shipping
• Specification: 500mg: 2ml
• Trademark: Customization
• Origin: China

Product Description

Value-added services:
 1) Packaging design by our team
 2) Registration service by our team
 3) Registration dossier available by our team
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Amikacin Injection 500mg/2ml

Composition:

Each 2ml vial contains:

• Amikacin Sulfate equivalent to Amikacin 500mg

Description:

Amikacin is an aminoglycoside antibiotic with broad-spectrum activity against Gram-negative and some Gram-positive bacteria. It works by inhibiting bacterial protein synthesis, leading to bacterial cell death.

Indications:

Amikacin Injection is indicated for the treatment of serious infections caused by susceptible bacteria, including:

• Severe respiratory tract infections (e.g., pneumonia, bronchitis)
• Complicated urinary tract infections (UTIs), including pyelonephritis
• Intra-abdominal infections (e.g., peritonitis)
• Bacteremia and septicemia
• Bone and joint infections (e.g., osteomyelitis)
• Skin and soft tissue infections
• Postoperative infections
• Neonatal sepsis

Dosage & Administration:

Adults & Adolescents (≥12 years):

• Usual dose: 15 mg/kg/day IV or IM, given as 7.5 mg/kg every 12 hours
• Severe infections: 15 mg/kg IV once daily

Pediatric Patients (≥1 month - 12 years):

• 15-22.5 mg/kg/day IV or IM in divided doses every 8-12 hours

Neonates & Premature Infants:

• Loading dose: 10 mg/kg IV or IM
• Maintenance dose: 7.5 mg/kg every 12 hours

Renal Impairment (Adults & Adolescents):

Creatinine Clearance (CrCl)	Dose	Dosing Interval
≥50 mL/min	Usual dose	Every 12 hours
20-50 mL/min	Usual dose	Every 24 hours
<20 mL/min	Half dose	Every 24-48 hours
Hemodialysis	5-7.5 mg/kg	After dialysis

Administration:

• Intramuscular (IM) injection: Deep intramuscular injection
• Intravenous (IV) infusion: Over 30-60 minutes
• Dilution: Use 0.9% Sodium Chloride (NS) or 5% Dextrose (D5W)

Contraindications:

• Hypersensitivity to Amikacin, other aminoglycosides.

Precautions:

• Nephrotoxicity risk - Monitor renal function.
• Ototoxicity risk - Monitor for hearing loss or tinnitus.
• Neuromuscular blockade - Caution in myasthenia gravis.
• Use in pregnancy - May cause fetal harm.

Adverse Reactions:

• Renal: Increased creatinine, nephrotoxicity.
• Neurological: Hearing loss, dizziness, vertigo.
• Gastrointestinal: Nausea, vomiting.
• Injection Site Reactions: Pain, inflammation.

Drug Interactions:

• Loop diuretics (e.g., furosemide): Increased ototoxicity risk.
• Neuromuscular blockers: Increased paralysis risk.
• Other nephrotoxic drugs (e.g., vancomycin, amphotericin B): Increased renal toxicity risk.

Storage Conditions:

• Store below 25°C, protect from light.
• Do NOT freeze.