| Customization: | Available |
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| Dosage Form: | Powder Injection |
| Dossier: | Ready |
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| Generic Name | Piperacillin Sodium and Sulbactam Sodium for Injection |
| Strength | 1.5g |
| Packing | 10 vials/box |
| Origin | China |
The indications are for the following infections caused by β-lactamase-producing bacteria that are resistant to piperacillin. Additional antibiotics are not necessary for the treatment of mixed infections caused by piperacillin sensitive bacteria and β-lactamase producing bacteria that are resistant to piperacillin and sensitive to piperacillin. 1. Respiratory infection: such as pneumonia, acute bronchitis, acute attack of chronic bronchitis, bronchiectasis with infection, acute lung abscess, bronchial asthma with infection, lung cyst with infection, etc. 2. Urinary system infection: including simple urinary system infection and complex urinary system infection.
Usage: intravenous infusion. Dissolve the product in appropriate amount (see table below) before use (5% glucose injection, 0.9% sodium chloride injection or sterile water for injection); Then diluted with the same solvent to 50-100 ml for intravenous infusion, the infusion time is 30-60 minutes.
Total dose (g) Total volume after water solution of Piperacillin + sulbactam (ml) Maximum final concentration (mg/ml)
2.5 2.0+0.5 10 200+50
Dosage: Adults 2.5g or 5g per session (i.e. piperacillin 2g or 4g, sulbactam 0.5g or 1g), once every 12 hours. For severe or refractory infections, 2.5g or 5g per dose (i.e. piperacillin 2g or 4g, sulbactam 0.5g or 1g) every 8 hours. Patients with renal insufficiency may adjust the dose as appropriate.
Course of treatment: 7 ~ 14 days, or according to the need to adjust the course of treatment.
1. Penicillin skin test should be done before medication.
2. Patients with renal insufficiency should be used with caution. Renal function should be monitored during medication. If abnormal renal function is found, the treatment plan should be adjusted in time.
3. Piperacillin may cause bleeding, and patients with bleeding tendencies should be checked for clotting time, platelet aggregation time and prothrombin time. The risk of bleeding increases when piperacillin sodium is combined with heparin, coumarin, indandione and other anticoagulants. Non-steroidal anti-inflammatory painkillers, platelet aggregation inhibitors, or sulpiridone combined with piperacillin sodium may also increase the risk of bleeding. If bleeding occurs, the drug should be stopped and appropriate treatment measures should be taken. Severe bleeding may occur when piperacillin sodium is combined with a thrombolytic agent, so it should not be used together.
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