GMP Certified / Erythromycin Lactobionate for Injection 1g

• Quality Standard: USP, Bp
• Usage Mode: Injection
• Factory Certified: GMP
• Transport Package: Carton
• Specification: 1g
• Trademark: Sinolead
• Model NO.: injection
• Origin: China
• Production Capacity: 100000ctns Per Month

Product Description

Generic Name	Erythromycin Lactobionate for Injection
Strength	1g
Packing	10 vials /box
Origin	China

 

 

Value-added services:
 Packaging design by our team
 Registration service by our team
 Registration dossier available by our team
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Product name:
Erythromycin Lactobionate for Injection

Character:
This product is white or quasi-white crystal or loose mass.

Indications:
1. This product is used as an alternative medicine for patients with penicillin allergy in the treatment of the following infections: acute tonsillitis, acute pharyngitis, and sinusitis caused by hemolytic streptococcus and streptococcus pneumoniae; Scarlet fever and cellulitis caused by hemolytic streptococcus; Diphtheria and diphtheria carriers; Gas gangrene, anthrax, tetanus; Actinomycosis; Syphilis; Listeriosis, etc.
2. Legionella disease.
3. Mycoplasma pneumonia.
4. Chlamydia pneumonia.
5. Other chlamydia, mycoplasma caused by genitourinary infection.
6. Chlamydia trachomatis conjunctivitis.
7. Gonococcal infection.
8. Oral infection caused by anaerobic bacteria.
9. Campylobacter jejuni enteritis.
10. Whooping cough.

Adverse reactions:
1. Gastrointestinal reactions were common, including diarrhea, nausea, vomiting, middle and upper abdominal pain, tongue pain, and decreased stomach appetite. The incidence was related to the dose.
2. Hepatotoxicity is rare. Patients may have fatigue, nausea, vomiting, abdominal pain, fever, abnormal liver function, and occasionally jaundice.
3. Large doses (≥4g/ day), especially in patients with liver and kidney diseases or elderly patients, may cause hearing loss, mainly due to high blood concentration (> 12mg/L) is associated with most recovery after discontinuation.
4. The allergic reaction manifested as drug fever, rash, eosinophilia, etc., the incidence was about 0.5% ~ 1%.
5. Other: Occasional arrhythmia, oral or vaginal candida infection

Pharmacology and toxicology:
This product is a macrolide antibiotic, which is a water-soluble erythromycin lacturonate. It has antibacterial activity against Staphylococcus, streptococcus and gram-positive bacillus in each group. Neisseria, Haemophilus influenzae, Bordetella pertussis, etc. can also be sensitive to this product. The product also has antibacterial activity against all kinds of anaerobic bacteria except Bacteroides fragilis and Fusobacterium. It also has inhibitory effects on Legionella, Campylobacter foetus, certain spirochaeta, Mycoplasma pneumoniae, Rickettsiae and Chlamydia. This strain is a bacteriostatic agent, but it also has bactericidal effect on some bacteria at high concentrations. The product can be reversibly bound to the 50S subunit of the bacterial ribosome near the donor site (" P "site) through the bacterial cell membrane, blocking the binding of the transfer ribonucleic acid (t-RNA) to the" P "site, and also blocking the shift of the polypeptide chain from the receptor site (" A" site) to the "P" site, thus inhibiting the bacterial protein synthesis. Erythromycin is only effective against actively dividing bacteria.

Storage:
Seal and store in a dry place.