| Generic Name |
Acyclovir Capsules USP 200mg |
| Strength |
200mg |
| Packing |
100 Tablets/bottle |
| Origin |
China |
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Packaging design by our team
Registration service by our team
Registration dossier available by our team
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Product name:
Acyclovir Capsules USP 200mg
Character:
This product is a capsule, the content is white to white powder.
Indications:
1. Herpes simplex virus infection: for primary and recurrent cases of genital herpes virus infection, oral use of this product for prevention of recurrent cases.
2. Shingles: For the treatment of shingles in people with normal immune function and mild cases of immune deficiency.
3. Treatment of chickenpox in immunodeficient patients.
Adverse reactions:
Occasionally dizziness, headache, joint pain, nausea, vomiting, diarrhea, stomach upset, loss of appetite, thirst, leukopenia, proteinuria and urea nitrogen slightly increased, skin itching, etc., long-term administration of the drug occasionally acne, insomnia, menstrual disorders.
Pharmacology and toxicology:
antiviral drug. It can inhibit herpes simplex virus, varicella zoster virus and cytomegalovirus in vitro. After entering herpes virus-infected cells, it competes with deoxyriboside viral thymidine kinase or cell kinase and is phosphorylated into activated acyclovir triphosphate, which then inhibits viral replication in two ways: (1) interfering with viral DNA polymerase and inhibiting viral replication; Under the action of DNA polymerase, it binds to the increased DNA chain, causing the extension of the DNA chain to be interrupted.
This product has a special affinity for viruses, but low toxicity to mammalian host cells. Carcinogenesis was reported by cell transformation assay in vitro, but no evidence of carcinogenesis was found in animal experiments. Some animal experiments have shown that high concentrations of drugs can cause mutations, but there is no evidence of chromosomal changes. The carcinogenic and mutagenic effects of this product are unclear. Large dose injection can cause testicular atrophy and reduced sperm count in animals, the drug can pass the placenta, and animal experiments have proved that it has no effect on embryos.
Storage:
Store tightly.
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